MEDONEFARMA
TOPOTECAN (POWDER)
PRODUCT DESCRIPTION
Topotecan is a type of chemotherapy drug called a topoisomerase 1 inhibitor. It works by blocking a chemical called topoisomerase 1. This chemical helps to separate and repair the DNA in cells when they divide. Cancer cells need to make and repair DNA in order to grow and multiply.
CHEMICAL NAME
(S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride.
Brand Names
Hycamtin
Category
Oncology (Injection)
DOSAGE FORM
Injection: Powder for injection. 4mg/4ml as single-use vial by intravenous infusion.
INDICATIONS
Topotecan monotherapy is indicated for the treatment of: • patients with metastatic carcinoma of the ovary after failure of first-line or subsequent therapy. patients with relapsed small cell lung cancer (SCLC) for whom re-treatment with the first-line regimen is not considered appropriate.
NDC CODE
0409-0302-01
STORAGE & SHELF LIFE
- Shelf life: 3 years (36 months)Unreconstituted.
- Store refrigerated between 2°C and 8°C (36°F and 46°F) in the original carton to protect from light
Anti-infectives
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